Friday, December 18, 2015

Glimperide.. Well absorbed from the intestine and is metabolized by the liver into ineffective compounds



Gelimbraad drug absorbed well from the intestine, and is metabolized by the liver into ineffective compounds are taken out through the urine. The half-life of the drug is 5-9 hours and the duration of effect in the body 12-24 hours.  
Therapeutic dose:
Usually given   Drug Algelimbraad dosage form once a day, either alone or in combination with insulin for diabetics who can not control their sugar levels through diet and sport. This medication leads to a decrease in the level of blood sugar lower dose than any other compound of drugs sulfonylureas, where studies have shown that only 1 mg of the drug has the ability to reduce the level of sugar in the blood.
The maximum dose recommended daily equivalent to 8 mg. In addition to the alert insulin secretion from beta cells, characterized by the property Algelimbraad slight reduction of insulin resistance and thus may be less inclined to cause a sharp drop in blood sugar than other drugs sulfonylureas. And also considered safer in people who suffer from a severe lack of kidney function and who have their creatinine level is high. Usually not recommended to use drugs other sulfonylureas in patients who have their creatinine levels high. Also, this drug does not prevent the natural process of extroversion of blood vessels does not affect the coronary arteries. These side effects may occur with other sulfonylureas drugs albeit rarely.