Thursday, June 15, 2023

Tolazamide.. Antihypertensive effect of sugar in the blood a little like chlorpropamide


Drug Tolazamide slowly absorbed from the intestine compared with other drugs of sulfonylureas. Has the effect of a little like chlorpropamide but shorter effect (within 12-14 hours), like Alasatohecsamed. And requires the effect of reducing   Blood sugar several hours. It is metabolized by the liver to several vehicles also have effect lowers blood sugar as well as other compounds are ineffective. The half-life of about 7 hours.

Therapeutic dose:

There in the form of tablets 100 mg and 250 mg and 500 mg
If the need arises for the use of more than 500 mg per day to reduce the level of sugar in the blood, it must divide the dose and give it   Twice a day. Doses greater than 1000 mg per day do not give the best result in regard to the control of blood sugar.