Wednesday, December 30, 2015

Diabetes and death.. Increase in the proportion of deaths at the most control blood sugar



In the study (ACCORD) researchers found that the death rate in the first group (the most control blood sugar) is higher than the death rate in the placebo group. And this after 3.5 years of research. But why this increase in the mortality rate of patients with the most control over blood sugar?.. Researchers have speculated in this study That the increase in the mortality rate for the group most control blood sugar may be due to: 
● The difference in the value of cumulative analysis of blood sugar or hemoglobin A1c  In the first group
The most control blood sugar rate cumulative blood sugar to 6.4% compared to the second set, which reached 7.5%. 
● May be due not only to the values ​​obtained from the analysis of the cumulative blood sugar, but the pace of decline cumulative analysis of blood sugar in the first group   Lowered cumulative analysis of blood sugar value of 1.4% in the first four months of the beginning of the search, compared with 0.6% in the first four months of the beginning of the search for the second group. 
● Maybe it's because the difference in the treatment regimen for the two groups. 
● Maybe it's because the increase in the incidence of hypoglycemia in the group most control blood sugar compared to the second set. 
● May be the reason for unwanted interference of the drugs that were used in high doses in the first set and that we do not know yet. 
● Or perhaps why a mixture of the above factors, taking into account also the nature of the cases that have been included in this research. 
Or in other words brief.. Did not know researchers to study why In excess mortality in this important study. 
The researchers concluded that   Conclusion   Of this study is:"This study showed that There harm of intensive good control Very Blood sugar Infected with type II diabetes and who are prone to diseases of the arteries and blood vessels, this injury may be the result of the pace of decline cumulative analysis of blood sugar, or to the same values ​​reached by the cumulative analysis of blood sugar "." 
As for The Advance Study (ADVANCE)   The researchers concluded for this study  Conclusion   Next: "" In the case of good control and get the value of the cumulative analysis of blood sugar at a rate of 6.5% we can get a relatively low value    10%    Per complications resulting from diabetes including vascular complications and heart. These interest as a result of the relative decline of kidney complications by 21% ""   Given the results of a study of (ACCORD), the researchers to study the (ADVANCE) indicated that what Reached is that it is not Influence of the quality control blood sugar in the mortality rate for any reason, as well as deaths from heart disease and blood vessels between Groups. 
So the contrast between the results of the study (ACCORD) and the results of the study (ADVANCE) continues and persists. There is no obvious reason why excess mortality in the Eokord study (ACCORD). 
Now to the important point of interest to the patient with type II diabetes and physician, after the results of these studies   Is there a suggestion   Last cumulative value analysis of blood sugar that diabetics must be accessed and targeted? .... Knowing that the previously proposed value is less than 7% ... Is not it? ... So is there a suggestion for other value? This is what we learn in Part III of this letter.