Thursday, December 24, 2015

Mechanism of action of drugs sulfonylureas.. Alert secretion of insulin from the beta cells in the pancreas

This is the basis for the mechanism of action of all drugs sulfonylureas. And be alert insulin secretion from beta cells by the union of these drugs with future T. beta cells. The union of these drugs in this way prevents potassium ions exit through the channels and result in the demise of polarization depolarization .This in turn opens calcium channels and lead to calcium entry and exit of insulin ready within cells. And confirms the validity of this theory that these drugs is not effective in patients who lack the presence of insulin, or even animals that have been the destruction of beta cells using chemical Alluxan alloxan .