Wednesday, May 31, 2023

Generic and trade names of anti malarial drugs



Generic and trade names of anti malarial drugs:

  • Cloroquine = Malarex & resochin.
  • Primaquine = Primaquine.
  • Pyremethamine + Sulfadoxine = Pansidar.

Medicines against malaria:

Quinine, chloroquine, amodiaquine, pyrimethamine, sulfadoxine, mefloquine, primaquine, artemisin and its derivatives, proguanil, halofantrine, doxycycline and clindamycin are all medications used alone or in different combinations to treat or prevent malaria.

Halofantrine:

Halofantrine (marketed under several trade names on average) is widely used in many places to treat malaria. It is not used to prevent malaria due to the risk of toxicity and reliable absorption.
Recently, malaria strains resistant to all known drugs, including artemisin and its derivatives, have been identified along the Thai / Myanmar border (Burma).

prevention of malaria:

For the prevention of malaria while traveling in a malaria area, the most commonly recommended medications are Malarone (atovaquone / proguanil) or doxycycline. However, it is important to keep in mind that different strains of malaria occur in different parts of the world and the type of medication prescribed must match the part of the world they are visiting. No antimalarial drug is 100% efficient and should be combined with the use of personal protective measures such as insect repellents, long sleeves, long pants, sleeping in a mosquito-free environment or using a mosquito net covered with insecticide.

Malarone:

It is the trade name for atovaquone and proguanil. It is effective for all parts of the world. The adult dose is usually a daily tablet, starting one or two days before traveling to an area that contains malaria. The dose should continue throughout the stay and then for another 7 days after leaving the area with malaria. The dose for a child is usually prescribed according to their body weight. Users should check with their doctor. Malarone should be taken with a fatty meal or milk to be properly absorbed.

Malarone:

Malarone is generally the option for short trips to areas with malaria because it generally produces much less side effects than other malaria drugs. Some people may experience side effects such as cough, headache, loss of appetite, mouth sores, nausea, stomach ache, diarrhea, vomiting, weakness and dizziness.

Doxycycline:

Doxycycline is an antibiotic that prevents the development of parasites in the blood that cause malaria.
To prevent malaria, the recommended dose of doxycycline is 1 to 2 days before traveling to an area where malaria is present, daily while in that area and daily for 4 weeks after leaving the area. It is better to take the tablets with food. Doxycycline is often cheaper than Malarone and for this reason they can be prescribed for long trips in an area endemic to malaria.

Side  effects of doxycycline:

Side effects of doxycycline may include: anorexia, nausea, diarrhea, candidiasis, tongue pain (glossitis), headaches, blurred vision or buzzing. The side effect of erythema (sunburn) due to photosensitivity to sunlight is especially important for those with the intention of long-term use for malaria prevention.