Which of the following is not an indication for Tranexamic Acid?
- a- Treatment of heamorrhage associated with excessive fibrinolysis
- b- An antidote for Streptokinase overdose
- c- Prophylaxis of hereditary angioedma
- d- Prevent heammorhage due to Heparin overdose.
The answer is b- An antidote for Streptokinase overdose.
Tranexamic acid is an antifibrinolytic agent that works by slowing the breakdown of fibrin, a protein that is essential for blood clotting. It is used to treat or prevent bleeding in a variety of situations, including:
- Heavy menstrual bleeding
- Postpartum hemorrhage
- Bleeding after surgery
- Bleeding due to trauma
- Hereditary angioedema
Streptokinase is a thrombolytic agent, which means it breaks down blood clots. It is used to treat heart attacks and strokes. Tranexamic acid is not an antidote for streptokinase overdose.
The other options are all indications for tranexamic acid:
- Treatment of hemorrhage associated with excessive fibrinolysis:
Tranexamic acid is effective at reducing bleeding in patients with excessive fibrinolysis, which is a condition in which the body breaks down blood clots too quickly.
- Prophylaxis of hereditary angioedma:
Tranexamic acid is used to prevent attacks of hereditary angioedema, a rare genetic disorder that causes swelling of the skin, mucous membranes, and gastrointestinal tract.
- Prevent hemorrhage due to Heparin overdose:
Tranexamic acid is used to prevent bleeding in patients who have overdosed on heparin, an anticoagulant medication.
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pharmacology