An agent that would be most likely to cause drugs- induced bronchospasm is:
- A) nedocromil
- B) Enalapril
- C) Isoproterenol
- D) Pindolol***
- E) Theophylline.
The agent most likely to cause drug-induced bronchospasm is D) Pindolol.
Here's why:
- Pindolol:
This is a non-selective beta-blocker medication used to treat hypertension and angina. Beta-blockers are known to cause bronchospasm in individuals with asthma or other underlying airway hyperactivity. This is because they block beta-2 receptors in the airways, leading to smooth muscle contraction and narrowing of the airways.
- Nedocromil:
This is a mast cell stabilizer used to prevent asthma attacks. It is not known to cause bronchospasm.
- Enalapril:
This is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and heart failure. ACE inhibitors can cause cough as a side effect, but bronchospasm is less common.
- Isoproterenol:
This is a beta-2 agonist medication used to treat asthma and other respiratory conditions. It relaxes the airways and is not likely to cause bronchospasm.
- Theophylline:
This is a bronchodilator medication used to treat asthma and chronic obstructive pulmonary disease (COPD). It is not known to cause bronchospasm.
Therefore, based on the potential side effects of each medication, Pindolol is the most likely to cause drug-induced bronchospasm.
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