When caring for a male client with acute renal failure (ARF), Nurse Fatima expects to adjust the dosage or dosing schedule of certain drugs. Which of the following drugs would not require such adjustment?
a. acetaminophen (Tylenol)
b. gentamicin sulfate (Garamycin)
c. cyclosporine (Sandimmune)
d. ticarcillin disodium (Ticar)
Answer A.
Because acetaminophen is metabolized in the liver, its dosage and dosing schedule need not be adjusted for a client with ARF. In contrast, the dosages and schedules for gentamicin and ticarcillin, which are metabolized and excreted by the kidney, should be adjusted. Because cyclosporine may cause nephrotoxicity, the nurse must monitor both the dosage and blood drug level in a client receiving this drug.
a. acetaminophen (Tylenol)
b. gentamicin sulfate (Garamycin)
c. cyclosporine (Sandimmune)
d. ticarcillin disodium (Ticar)
Answer A.
Because acetaminophen is metabolized in the liver, its dosage and dosing schedule need not be adjusted for a client with ARF. In contrast, the dosages and schedules for gentamicin and ticarcillin, which are metabolized and excreted by the kidney, should be adjusted. Because cyclosporine may cause nephrotoxicity, the nurse must monitor both the dosage and blood drug level in a client receiving this drug.
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