Causes Irritable Bowel Syndrome.. Misuse of food. Growing affluence and lack of movement. Stress, anxiety and depression. Adverse climatic conditions NIL NAM December 15, 2015 Causes of irritable bowel disease not yet reveal the exact, but are likely to be the following reasons: ** Misuse of food. * Growing affluence and lack of movement. ** Stress, anxiety and depression. * Adverse climatic conditions. Share This: Facebook Twitter Google+ Stumble Digg