ß1 agonist cause:
- A- Increase in oxygen consumption.
- B- Increasing ectotopic effect.
- C- Increasing intotopic effect.
- D- All of the above.
The answer is D. All of the above.
ß1 agonists, which bind to beta-1 receptors primarily found in the heart, can cause all of the listed effects:
- Increase in oxygen consumption:
Activation of beta-1 receptors stimulates the heart to contract more forcefully and at a faster rate. This increased cardiac output requires more oxygen for the heart muscle to function properly.
- Increasing ectotopic effect:
Ectotopic foci are abnormal areas in the heart that can initiate an irregular heartbeat. Stimulating beta-1 receptors can increase the firing rate of these foci, potentially leading to arrhythmias like tachycardia or atrial fibrillation.
- Increasing intotopic effect:
While less common, ß1 agonists can also directly increase the excitability of the heart's normal pacemaker, the sinoatrial node, leading to a faster heart rate (positive inotropic effect).
Therefore, all three effects can occur upon administration of ß1 agonists, although their specific impact and potential risks will depend on various factors like the type of ß1 agonist, dosage, and the individual's health conditions.
It's important to note that ß1 agonists are typically used for specific medical purposes under controlled settings due to their potential side effects. They should not be used without a doctor's prescription.
