All of the following statements about propranolol are true except:
- a- The oral route of administration is preferred
- b- Propranolol penetratesin to the CNS
- c- Propranolol is primarily biotransformed in the liver
- d- Propranolol causes rashes and sore throut
- e- It is non selective alpha antagonist.
The statement that is not true about propranolol is: e. It is a non-selective alpha antagonist.
Here's why:
a. The oral route of administration is preferred:
This is true. Propranolol is typically taken orally due to its good bioavailability and absorption in the gastrointestinal tract.
b. Propranolol penetrates into the CNS:
This is also true. Propranolol can cross the blood-brain barrier and exert its effects on the central nervous system, contributing to its potential for side effects like anxiety or dizziness.
c. Propranolol is primarily biotransformed in the liver:
This is true as well. Propranolol undergoes extensive metabolism in the liver before being eliminated from the body.
d. Propranolol causes rashes and sore throat:
While rashes and sore throat can be potential side effects of propranolol, they are not as common as other side effects like fatigue, dizziness, or bradycardia.
e. It is a non-selective alpha antagonist:
This is not true. Propranolol is a beta-blocker and does not have significant alpha-blocking properties. It primarily acts on beta-adrenergic receptors, affecting heart rate, blood pressure, and other physiological functions.
Therefore, the incorrect statement is e. Propranolol is a beta-blocker, not a non-selective alpha antagonist.
