Friday, January 26, 2024

If you have prescription containing Inderal & the patient is wheezing, what is your advice - Patient has hepatic disease & type II diabetics take

- If you have prescription containing Inderal & the patient is wheezing, what is your advice?

  • Call the doctor.

- Patient has hepatic disease & type II diabetics take:    

  • Rosiglitazone or piaglitazone (Avandia, Glustin).
You're correct on both points:

1. Inderal and wheezing:

If a patient taking Inderal (propranolol) is wheezing, it's critical to call the doctor immediately. Inderal can worsen bronchospasm (wheezing) in patients with asthma or other respiratory conditions. This can be a serious medical emergency requiring prompt medical attention.

2. Hepatic disease and type II diabetes:

Rosiglitazone and pioglitazone (Avandia and Glustin) are not recommended for patients with severe hepatic disease due to the risk of liver damage. Therefore, these medications would not be the first-line choice for a patient with both hepatic disease and type II diabetes.

Alternative Medication Options:

Here are some alternative medication options for this patient, depending on the severity of their liver disease and other individual factors:

- Metformin:

Often the first-line choice for type II diabetes, particularly if overweight or obese.

- DPP-4 inhibitors:

Examples include sitagliptin (Januvia) and liraglutide (Victoza). These medications work by increasing the release of insulin from the pancreas and decreasing glucagon production.

- SGLT2 inhibitors:

Examples include empagliflozin (Jardiance) and canagliflozin (Invokana). These medications work by helping the kidneys remove excess glucose from the blood through urine.

The specific medication choice should be made by a qualified healthcare professional after considering the patient's individual circumstances, including co-existing medical conditions, medication interactions, and overall health.


Never adjust or discontinue any medication without consulting a doctor.
Always disclose all medical conditions and medications to healthcare professionals.
Seek immediate medical attention if you experience any concerning symptoms while taking medication.