Estimation of G6PDH is a test to:
- A- Measure blood glucose.
- B- To diagnose hemolytic anemia.
- C- To diagnostic myocardial infraction.
- D- To diagnostic pancreatic disease.
The correct answer is B. To diagnose hemolytic anemia.
Here's why:
- Glucose-6-phosphate dehydrogenase (G6PDH) is an enzyme found in red blood cells that helps protect them from damage.
- Hemolytic anemia is a condition where red blood cells are destroyed faster than they can be produced, leading to symptoms like fatigue, jaundice, and shortness of breath.
- G6PD deficiency is a genetic condition where the body lacks enough G6PDH enzyme. This deficiency can make red blood cells more susceptible to damage, leading to hemolytic anemia.
Therefore, estimating G6PDH activity is primarily used to:
- Diagnose G6PD deficiency
- Identify individuals at risk for hemolytic anemia
- Monitor the severity of hemolytic anemia caused by G6PD deficiency.
Other Options:
Here's a breakdown of the other options:
A. Measure blood glucose:
While G6PDH plays a role in metabolism, it's not directly involved in blood glucose regulation. Blood glucose levels are typically measured with a different test, like a fasting blood sugar or hemoglobin A1c test.
C. Diagnose myocardial infarction:
Myocardial infarction, commonly known as a heart attack, is caused by a blockage in the coronary arteries that supply blood to the heart muscle. G6PDH deficiency is not directly related to heart problems.
D. Diagnose pancreatic disease:
The pancreas is responsible for producing digestive enzymes and hormones, including insulin and glucagon, which regulate blood sugar. G6PDH deficiency is not associated with pancreatic dysfunction.
