Which of the following is (are) a property or an action of pilocarpine?
- 1. Direct acting miotic
- 11. Ingredient in Ocusert ocular therapeutic system
- 111. Similar pharmacologic action to dorozolamide (Trusopt)
- A) 1 only
- B) 111 only
- C) 1 and 11 only***
- D) 11 and 111 only
- E) 1,11 and111
The correct answer is C) 1 and 11 only. Here's why:
1. Direct acting miotic:
This is true. Pilocarpine is a miotic, meaning it constricts the pupil. It does this by acting directly on the muscarinic receptors in the iris sphincter muscle.
11. Ingredient in Ocusert ocular therapeutic system:
This is also true. Ocusert is a brand name for a slow-release ocular insert containing pilocarpine.
111. Similar pharmacologic action to dorozolamide (Trusopt):
This is false. Dorozolamide is a carbonic anhydrase inhibitor, which works by reducing the production of aqueous humor in the eye, thereby lowering intraocular pressure. Pilocarpine, on the other hand, increases the outflow of aqueous humor, leading to the same result, but through a different mechanism.
Therefore, only options 1 and 11 are properties or actions of pilocarpine.
other Options:
Here's a breakdown of the other options:
- A) 1 only: This is incorrect because option 11 is also true.
- B) 111 only: This is incorrect because option 111 is false.
- D) 11 and 111 only: This is incorrect because option 111 is false.
- E) 1,11 and 111: This is incorrect because option 111 is false.
