Sunday, February 11, 2024

Rhodic factor (Rh): Adhesion generators are found on the surface of red blood cells

Rhysus factor (Rh):

While Rh factor (Rh) is associated with antigens found on the surface of red blood cells, it is not accurate to say they are "adhesion generators."
Here's a breakdown:

Rh factor:

  • The Rh factor is a protein found on the surface of red blood cells.
  • Individuals who have this protein are Rh-positive, while those who lack it are Rh-negative.
  • The Rh factor is important in blood transfusions, as mismatched Rh types can lead to a severe immune reaction.

Antigens and antibodies:

  • Antigens are molecules that can trigger an immune response.
  • Antibodies are proteins produced by the immune system in response to antigens.
  • When an Rh-negative individual receives blood from an Rh-positive individual, their immune system may recognize the Rh protein as foreign and produce antibodies against it.
  • This can lead to a serious condition called hemolytic transfusion reaction, where the antibodies attack and destroy the transfused red blood cells.


  • Adhesion molecules are proteins found on the surface of cells that help them stick to other cells or to the extracellular matrix.
  • While Rh factor is present on the red blood cell surface, it is not primarily involved in adhesion. Its main function is related to the immune response, as mentioned above.

Therefore, it's more accurate to say that Rh factor is an antigen found on red blood cells that can trigger an immune response in individuals who lack it, rather than calling them "adhesion generators."