Thursday, January 18, 2024

An example of a 5-HT3 receptor antagonist is.. Ondanestron - Zofran



An example of a 5-HT3 receptor antagonist is:

  • A- Bromocryptine (Parlodel).
  • B- Cimetidine (Tagamet).
  • C- Ondanestron (Zofran).
  • D- Fluoxetine (Prozac).

The correct answer is C- Ondanestron (Zofran).

Here's why:

A- Bromocryptine (Parlodel):

is a dopamine agonist, primarily used for treating Parkinson's disease and hyperprolactinemia. It does not interact with 5-HT3 receptors.

B- Cimetidine (Tagamet):

is an H2 receptor antagonist, primarily used for treating heartburn and ulcers. It does not interact with 5-HT3 receptors.

C- Ondanestron (Zofran):

is a 5-HT3 receptor antagonist, commonly used to prevent and treat nausea and vomiting caused by chemotherapy, radiation therapy, and postoperatively.

D- Fluoxetine (Prozac):

is a selective serotonin reuptake inhibitor (SSRI), primarily used for treating depression and anxiety. It acts on different serotonin receptors than 5-HT3.

Therefore, Ondanestron (Zofran) is the specific example of a 5-HT3 receptor antagonist, while the other options act on different receptors or have different targets.