A male client has recently undergone surgical removal of a pituitary tumor. Dr. Wong prescribes corticotropin (Acthar), 20 units I.M. q.i.d. as a replacement therapy. What is the mechanism of action of corticotropin?
a. It decreases cyclic adenosine monophosphate (cAMP) production and affects the metabolic rate of target organs.
b. It interacts with plasma membrane receptors to inhibit enzymatic actions.
c. It interacts with plasma membrane receptors to produce enzymatic actions that affect protein, fat, and carbohydrate metabolism.
d. It regulates the threshold for water resorption in the kidneys.
Answer C.
Corticotropin interacts with plasma membrane receptors to produce enzymatic actions that affect protein, fat, and carbohydrate metabolism. It doesn’t decrease cAMP production. The posterior pituitary hormone, antidiuretic hormone, regulates the threshold for water resorption in the kidneys.
a. It decreases cyclic adenosine monophosphate (cAMP) production and affects the metabolic rate of target organs.
b. It interacts with plasma membrane receptors to inhibit enzymatic actions.
c. It interacts with plasma membrane receptors to produce enzymatic actions that affect protein, fat, and carbohydrate metabolism.
d. It regulates the threshold for water resorption in the kidneys.
Answer C.
Corticotropin interacts with plasma membrane receptors to produce enzymatic actions that affect protein, fat, and carbohydrate metabolism. It doesn’t decrease cAMP production. The posterior pituitary hormone, antidiuretic hormone, regulates the threshold for water resorption in the kidneys.
