Non-steroidal anti-inflammatory drugs (NSAIDS) - such as salicylate, sulfa compounds, and warfarin - remove sulfonylurea drugs and increase their concentration in the blood and cause a sharp drop in blood sugar.
The second-generation sulfonyluria drugs are distinguished from first-generation drugs by not associating them with blood proteins.
Thus, a dramatic drop in blood sugar levels due to drug interactions with blood proteins is rare with second-generation sulfonylurea.
- Estrogen-containing pills can increase the effect of sulfonyluria drugs in a severe drop in blood sugar level.
Some antifungal drugs such as fluconazole and antibiotics such as chloramphenicol can lead to a severe hypoglycemia when used with sulfonyl urea drugs.
This is caused by the inhibition of sulfonyluria urea by these drugs and also by competing with blood proteins or with the output .
- Antihypertensive drugs can increase the risk of hypoglycemia when used with sulfonyl urea drugs.
- When using alcohol with sulfonyl urea drugs, this increases the risk of a severe drop in blood sugar.
The second-generation sulfonyluria drugs are distinguished from first-generation drugs by not associating them with blood proteins.
Thus, a dramatic drop in blood sugar levels due to drug interactions with blood proteins is rare with second-generation sulfonylurea.
- Estrogen-containing pills can increase the effect of sulfonyluria drugs in a severe drop in blood sugar level.
Some antifungal drugs such as fluconazole and antibiotics such as chloramphenicol can lead to a severe hypoglycemia when used with sulfonyl urea drugs.
This is caused by the inhibition of sulfonyluria urea by these drugs and also by competing with blood proteins or with the output .
- Antihypertensive drugs can increase the risk of hypoglycemia when used with sulfonyl urea drugs.
- When using alcohol with sulfonyl urea drugs, this increases the risk of a severe drop in blood sugar.
