IN WHICH CASE IS THE DRUG ACTIFEDSIGN PRESCRIBED?
This medication combines an antihistamine with a drying effect on nasal secretions, paracetamol, an antipyretic and analgesic , and vitamin C.
It is used to relieve runny nose, headache and/or fever during colds.
PRESENTATIONS OF THE DRUG ACTIFEDSIGN
COMPOSITION OF THE DRUG ACTIFEDSIGN
| p gel | |
| Chlorphenamine maleate | 3,2 mg |
| Paracetamol | 240 mg |
| Ascorbic acid ( vitamin C) | 100 mg |
CONTRAINDICATIONS OF THE DRUG ACTIFEDSIGN
liver failure ,
risk of angle-closure glaucoma ,
risk of urine blockage ( prostate adenoma ) .
ATTENTION
Paracetamol is present alone or in combination with other substances in many medicines: make sure you do not take several medicines containing paracetamol at the same time, because taking them together leads to a risk of overdose which can be toxic for the liver.
Due to the presence of an antihistamine with sedative and atropine properties , precautions are necessary in the event of severe renal insufficiency and in the elderly, in particular in the event of chronic constipation, prostate adenoma , tendency to dizziness or low blood pressure.
Chlorphenamine can cause acute glaucoma in predisposed people: red, hard and painful eye, with blurred vision. An extreme emergency consultation with an ophthalmologist is necessary.
Avoid alcoholic beverages: increased risk of drowsiness.
This medication can induce drowsiness, sometimes intense in some people. This drowsiness can be increased by taking alcohol or other sedative drugs . Driving and using dangerous machinery is strongly discouraged, especially in the hours after taking the medication.
INTERACTIONS OF THE DRUG ACTIFEDSIGN WITH OTHER SUBSTANCES
Tell your doctor or pharmacist if you are taking any other medication with atropine or sedative effects ( tranquilizers , sleeping pills , certain cough or pain medications containing opiates , antidepressants , neuroleptics , etc.).
In the event of treatment with an oral anticoagulant and with paracetamol at maximum doses (4 g per day) for at least 4 days, increased monitoring of the anticoagulant treatment may be necessary.
FERTILITY, PREGNANCY AND LACTATION
PREGNANCY :
Occasional use of this medication during pregnancy is possible, provided that the recommended dosage is observed. Nevertheless, its use in the days preceding childbirth must be reported to the doctor; in fact, special monitoring of the newborn may be necessary.
FEEDING WITH MILK :
This drug passes weakly into breast milk. As a precaution, its use is not recommended for breastfeeding women.
INSTRUCTIONS FOR USE AND DOSAGE OF THE DRUG ACTIFEDSIGN
The capsules must be swallowed as they are with a drink (water, milk, fruit juice, etc.), respecting an interval of at least 4 hours between doses. In case of severe renal insufficiency , it is necessary to space the catches of at least 8 hours.
In case of bothersome drowsiness, prefer taking in the evening.
USUAL DOSE:
Adult and child over 12 years old : 1 capsule, to be renewed if necessary after 4 hours, without exceeding 5 capsules per day.
TIPS
This treatment has no anti-infective effect. If the problems persist for more than 5 days, consult your doctor.
POSSIBLE SIDE EFFECTS OF THE DRUG ACTIFEDSIGN
Drowsiness.
Dry mouth, constipation , accommodation disorders , urinary retention.
Orthostatic hypotension , dizziness , tremors, agitation, confusion of ideas especially in the elderly.
Rarely: allergic reaction , abnormal blood count .
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