Glyburide (Glibenclamide).. Effectiveness too weak to reduce the level of sugar in the blood

Glyburide drug absorbed well when administered orally but unimpaired absorbed the existence food in the stomach And therefore can be taken with a meal. The advantage of this drug that in spite of his short half-life (less than 3 hours), but the effect lasts for a period of twenty-four hours after a single dose in the morning.

It is metabolized in the liver to have effective compounds too weak to reduce the level of sugar in the blood. And is directed by products of the metabolism of this drug for a way urine and bile.

Therapeutic dose:

And there in the form of tablets weighing 1.25 mg, 1.5 mg, 2.5 mg, 3 mg, 5 mg.

Usually given Aljlaepjurajd in initially at a dose of 2.5 mg per day or less. The average dose of between 5-10 mg per day, given in the form of a single dose in the morning. Not recommended to use higher doses of 20 mg per day.

This drug does not result in the detention of the fluids in the body, as happens with but Alklorbrupamid on the contrary cause lucrative Paul albeit slightly.

Not recommended to use this drug in patients with impairment of liver function or patients who suffer from a deficiency in kidney function.