Action of Strept. Pyogene is through:
- [A] Hyalurinidase.
- [B] Streptokinase.
- [C] Staf kinase.
- [D] Coagulase.
The correct answer is: B) Streptokinase.
Streptokinase is an enzyme produced by Streptococcus pyogenes (Strep. pyogenes) bacteria. It acts by converting plasminogen (an inactive protein in the bloodstream) to plasmin (an active enzyme). Plasmin then breaks down fibrin, a key component of blood clots. This clot-busting activity of streptokinase contributes to the invasiveness and virulence of Strep. pyogenes infections.
Here's why the other options are incorrect:
A) Hyaluronidase:
This enzyme is also produced by Strep. pyogenes and helps the bacteria spread through tissues by breaking down hyaluronic acid, a component of the extracellular matrix. However, its primary function is not directly related to clot formation or lysis.
C) Staf kinase:
This enzyme is produced by Staphylococcus aureus bacteria, not Strep. pyogenes. It also acts to break down fibrin, but it is distinct from streptokinase in its structure and function.
D) Coagulase:
This enzyme is also produced by Staphylococcus aureus and helps the bacteria form blood clots by converting fibrinogen (a soluble protein) to fibrin. It is not present in Strep. pyogenes.
Therefore, due to its specific function in dissolving blood clots and contributing to the spread of Strep. pyogenes infections, streptokinase is the correct answer.
