A female client with chronic obstructive pulmonary disease (COPD) takes anhydrous theophylline, 200 mg P.O. every 8 hours.
During a routine clinic visit, the client asks the nurse how the drug works. What is the mechanism of action of anhydrous theophylline in treating a nonreversible obstructive airway disease such as COPD?
- A. It makes the central respiratory center more sensitive to carbon dioxide and stimulates the respiratory drive.
- B. It inhibits the enzyme phosphodiesterase, decreasing degradation of cyclic adenosine monophosphate, a bronchodilator.
- C. It stimulates adenosine receptors, causing bronchodilation.
- D. It alters diaphragm movement, increasing chest expansion and enhancing the lung’s capacity for gas exchange.
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